| Pair Name | Propyl gallate, Temozolomide | ||
| Phytochemical Name | Propyl gallate (PubChem CID: 4947 ) | ||
| Anticancer drug Name | Temozolomide (PubChem CID: 5394 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Propyl gallate, Temozolomide | |||
| Disease Info | [ICD-11: 2A00] | Glioblastoma multiforme | Investigative | |
| Biological Phenomena | Inhibition-->ROS generation | |||
| Gene Regulation | Down-regulation | Phosphorylation | CHUK | hsa1147 |
| Down-regulation | Phosphorylation | IKBKE | hsa9641 | |
| Down-regulation | Activity | MMP2 | hsa4313 | |
| Down-regulation | Activity | MMP9 | hsa4318 | |
| Down-regulation | Phosphorylation | RELA | hsa5970 | |
| In Vitro Model | U-87MG ATCC | Glioblastoma | Homo sapiens (Human) | CVCL_0022 |
| Result | Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF- κ B Pathway | |||
| No. | Title | Href |
|---|---|---|
| 1 | Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF-κB Pathway. J Immunol Res. 2017;2017:9489383. doi: 10.1155/2017/9489383. | Click |
